Custom Peptides
Cayman Chemical StreptogramIn B 10mg
A macrolide antibiotic; inhibits the growth of Clostridium, Peptostreptococcus, and Propionibacterium bacterial species (MIC90s = 2, 0.5, and 8 μg/ml, respectively); inhibits protein synthesis by interacting with the 50S ribosome
Cayman Chemical 1MyrIstoyl2LInoleoyl3Ole 10mg
A triacylglycerol; has been found in mature human milk, infant formula fats, and butterfat
Cayman Chemical ADL5859hydrochlorIde 10mg
A δ-opioid receptor agonist (Ki = 0.84 nM); selective for δ-opioid receptors over μ-opioid and κ-opioid receptors at 10 μM; completely reverses CFA-induced mechanical hyperalgesia in rats at 3 mg/kg; decreases immobility time in the forced swim test in rats
Cayman Chemical XamoterolhemIfumarate 10mg
A β1-adrenergic receptor partial agonist (EC50 = 80 nM for the generation of cAMP in neonatal rat cardiomyocyte cultures); increases spontaneous contraction of isolated rat right atria (EC50 = 4.67 nM); increases heart rate in beagle dogs (ED50 = 3.2 UG/kg) and a rat model of spontaneous heart failure (ED50 = 6 UG/kg)
Cayman Chemical nmonaprde 10mg
An antipsychotic that binds D2-like receptors preferentially over D1-like receptors (Kis = 0.06, 0.3, and 0.15 nM for D2, D3, and D4, respectively); also binds σ1 and σ2 receptors (Kis = 8.4 and 9.6 nM, respectively) and activates the 5-HT1A receptor (IC50 = 34 nM)
Cayman Chemical GlucosamIn Cholesterol 10mg
A glucosamine-based lipid conjugate; has been used in the formation of LNPs; forms a stable, ordered bilayer with the glucosamine moiety facing outward to facilitate recognition by GLUT1 on cells; LNPs containing glucosamine cholesterol and encapsulating ceramide induce apoptosis in hypoxic human A549 cells and A549-derived side population cells but not hypoxic mouse L-929 fibroblasts; LNPs containing glucosamine cholesterol and encapsulating paclitaxel and carboplatin reduce tumor volume and increase tumor-associated cytotoxic T cells in an LL/2 murine lung carcinoma model
Cayman Chemical 12keto Chenodeoycholc ACD 10mg
An intermediate in the synthesis of ursodeoxycholic acid and chenodeoxycholic acid; has been found in the gastric tissues of C57BL/6J mice, KM mice, Sprague-Dawley rats, New Zealand white rabbits, and JX black pigs; fecal levels are increased in children with hepatic glycogen storage disease; the sodium salt form, 12-MKA, increases brain uptake of quinine, the analgesic effect of morphine in the hot plate test, and pentobarbital-induced sleeping time in rats at 2 mg/kg; 12-MKA promotes nasal absorption of insulin and increases the duration of local anesthesia induced by lidocaine in rats
Cayman Chemical BrIvnIb AlnInate 10mg
A prodrug form of brivanib; reduces hepatic angiogenesis and VEGF, TGF-β1, CD31, and phosphorylated VEGFR2 and FGFR levels in a bile duct-ligated rat model of cirrhosis at 3 mg/kg per day; reduces tumor growth in an L2987 non-small cell lung cancer mouse xenograft model, exhibiting 97% tumor growth inhibition at 107 mg/kg
Cayman Chemical Salva plba . B. spduln 10mg
A flavonoid with diverse biological activities; inhibits PAF-, arachidonic acid-, and ADP-induced platelet aggregation (IC50s = 20, 4, and 13 μM, respectively); inhibits RANKL-induced osteoclastic differentiation of RAW 264.7 cells and BMMs; inhibits LPS-induced bone resorption in mice at 25 μg/kg; inhibits tumor growth in a Caki-2 mouse xenograft model; reduces sevoflurane-induced cognitive deficits in aged rats at 40 mg/kg; decreases infarct size and brain edema in a rat model of focal cerebral ischemia and reperfusion injury
Cayman Chemical AcrIdIn Ornge 10-nonylbro 10mg
A mitochondrial dye; incorporates into the cardiolipin-rich inner mitochondrial membrane; selectively binds to cardiolipin-containing liposomes over phosphatidylserine- and phosphatidylinositol-containing liposomes in vitro (Kas = 0.002, 7,000, and 7,000 mM, respectively); binding dependent on mitochondrial membrane potential; ex/em = 490/510 nm, respectively; has been used to quantify cardiolipin content and mitochondrial mass in isolated mitochondria and cellular systems
Cayman Chemical LnIfIbrnor 10mg
A PPAR agonist (EC50s = 1,537, 866, and 206 nM for human recombinant PPARα, PPARβ, and PPARγ, respectively); increases β-oxidation in Huh-7 and C2C12 cells at 1 and 3 µM, respectively; reduces plasma glucose and triglyceride levels in a db/db mouse model of type 2 diabetes at 10 and 30 mg/kg for five days; increases plasma adiponectin levels and decreases collagen deposition in a carbon tetrachloride-induced mouse model of NASH
Cayman Chemical DecnoIc AcId-d19 10mg
An internal standard for the quantification of decanoic acid by GC- or LC-MS
